Main Research Themes
Drivers of Myeloid Malignancies
Determine the genetic mutations that drive myeloid malignancies, the clinical consequences of specific mutations, and the biological basis of transformation. |
Clonal Hematopoiesis of Indeterminate Potential
Understand the genetics of pre-malignant states for blood cancers and the effects of these pre-malignant states on the development of both cancer and non-malignant diseases. |
Therapeutic Targeting of Protein Degradation
Explore the development of novel therapeutics that modulate ubiquitin ligase activity to induce targeted protein degradation. |